Job Description
Summary
We are seeking a highly motivated Staff Scientist to lead and advance research using human-derived experimental models of disease, including iPSC-based systems, organoids, and multi-tissue platforms. The Staff Scientist will play a central role in experimental design, execution, data integration, and mentoring, while ensuring rigor, reproducibility, and continuity across complex, long-term projects. This position is ideal for a scientist who enjoys deep scientific ownership, collaboration across disciplines, and translating human biology into mechanistic insight and therapeutic relevance.
Job Duties
- Design, execute, and optimize experiments using human cellular models of disease, including iPSCs, brain organoids, and engineered tissue systems
- Lead day-to-day scientific operations for one or more research thrusts, ensuring technical excellence and reproducibility
- Integrate multi-modal datasets (e.g., transcriptomics, metabolomics, imaging, functional assays) in collaboration with computational and analytical teams
- Mentor trainees (students, technicians, postdocs) in advanced experimental techniques and scientific reasoning
- Develop and maintain standardized protocols, quality control pipelines, and documentation for human model systems
- Contribute substantially to manuscripts, grant applications, and progress reports
- Collaborate closely with clinicians, bioengineers, computational scientists, and external partners
- Support translational efforts, including disease modeling, biomarker discovery, and therapeutic testing
- Perform other job related duties as assigned
Minimum Qualifications
- Doctoral Degree. Experience may not be substituted in lieu of degree.
- Three years of post doctoral research experience.
Preferred Qualifications
- PhD (or MD/PhD) in neuroscience, cell biology, stem cell biology, or a related field
- Extensive hands-on experience with human iPSC-derived models and/or organoids
- Experience with disease modeling, neurodevelopmental or neurodegenerative disorders, or metabolic disease
- Familiarity with multi-omics approaches, spatial biology, or advanced imaging
- Experience working in interdisciplinary environments bridging basic science and translational research
- Prior contributions to high-impact publications and funded projects
- Strong background in experimental design, data interpretation, and scientific writing
- Demonstrated ability to work independently while contributing to team-based science
- Commitment to rigor, reproducibility, and mentorship
Work Authorization Requirement:
This position is not eligible for visa sponsorship. Candidates must be legally authorized to work in the United States at the time of application and throughout the duration of employment.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.
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